Bone-forming cells originate from __________.

Oct 30, 2023 · 1/3. Synonyms: none. Osteoblasts are bone-forming cells derived from osteoprogenitor stem cells which arise from mesenchymal tissue. They are mostly located in the periosteum and the endosteum but may also occur within compact bone, in regions of remodeling. Histologically, active osteoblasts, which are engaged in bone matrix synthesis, appear ... Within the bone marrow, all blood cells originate from a single type of unspecialized cell called a stem cell. When a stem cell divides, it first becomes an immature red blood cell, white blood cell, or platelet-producing cell. The immature cell then divides, matures further, and ultimately becomes a mature red blood cell, white …The bone marrow provides a framework of microenvironmental domains or niches that support the function of immune cells and haematopoietic stem cells (HSCs). Cellular niches are functional ...Functioning as vital cells in the bone matrix that maintains adequate bone mineral density through stimulating bone turnover and maintaining plasma calcium levels, osteoclasts are multinucleate cells that arise from hematopoietic stem cells.[1][2][3][4] As a result, they are identifiable with the presence of CD13, …The latter originate from the ... (or infamous) human embryonic stem cells, but with HSCs, which have been used in human therapy (such as bone marrow transplants ... The distribution of colony-forming cells among spleen colonies. J Cell Comp Physiol 1963, 62(3): 327-336 [] Evans, M. J. and Kaufman, …Nov 27, 2019 · Osteoclasts originate from hematopoietic stem cells (HSC), which are contained in the bone marrow. These are the same stem cells which produce all other types of blood cell, including red blood ... Within the bone marrow, all blood cells originate from a single type of unspecialized cell called a stem cell. When a stem cell divides, it first becomes an immature red blood cell, white blood cell, or platelet-producing cell. The immature cell then divides, matures further, and ultimately becomes a mature red blood cell, white blood cell, or ... Primary bone cancer (PBC) is a rare malignant tumor of the bone, originating from primitive mesenchymal cells. It accounts for around 0.2% of all malignancies worldwide and is idiopathic in most cases. There are multiple subtypes, with osteosarcoma, chondrosarcoma, and Ewing sarcoma, the most common. …2.1. Osteoclasts. Osteoclasts, the unique cells involved in bone resorption, originate from myeloid cells of the monocyte/macrophage lineage. Osteoclastogenesis is a multistep process, in which first osteoclast precursors differentiate into mononuclear pre-osteoclast, which then fuse into multinucleated …The blood-forming stem cells in red bone marrow can multiply and mature into three significant types of blood cells, each with its own job: ... These cells originate from hematopoietic stem cells ... Within the bone marrow, all blood cells originate from a single type of unspecialized cell called a stem cell. When a stem cell divides, it first becomes an immature red blood cell, white blood cell, or platelet-producing cell. The immature cell then divides, matures further, and ultimately becomes a mature red blood cell, white blood cell, or ... The cells responsible for bone resorption, or breakdown, are the osteoclasts. These multinucleated cells originate from monocytes and macrophages, …Bone ossification, or osteogenesis, is the process of bone formation. This process begins between the sixth and seventh weeks of embryonic development and continues until about age twenty-five; although this varies slightly based on the individual. There are two types of bone ossification, intramembranous and endochondral. Each of …The cells responsible for bone resorption, or breakdown, are the osteoclasts. These multinucleated cells originate from monocytes and macrophages, …Development of mast cells from uncommitted bone marrow-derived stem and progenitor cells. In adult humans, most hematopoietic stem cells (HSC) and mast cell-committed progenitor cells (cells depicted as containing only one cytoplasmic granule in this figure) are considered to originate from the bone …Bone remodeling is a process in which old or damaged bone is removed by osteoclasts and replaced with new bone formed by osteoblasts. Osteoclasts, bone-resorbing cells, originate from hematopoietic stem cells (HSCs) [4–8] and degrade bone via secretion of acid and proteolyticFour types of bone cells are osteoblasts, osteocytes, osteoclasts, and bone lining cells. Osteoblasts are formed from osteogenic or osteoprogenitor cells, and further transform into osteocytes ...Murine ES cells cultured as embryoid bodies in vitro contain blast colony-forming cells that form both endothelial and hematopoietic cells upon secondary replating [12]. The absence of yolk-sac blood islands in mutant mouse embryos lacking flk-1 provides further evidence suggesting that endothelial cells …Osteosarcoma signs and symptoms most often start in a bone. The cancer most often affects the long bones of the legs, and sometimes the arms. The most common symptoms include: Bone or joint pain. Pain might come and go at first. It can be mistaken for growing pains. Pain related to a bone that breaks for no …Among the three embryonic germ layers, the mesoderm is a major source of the mesenchymal precursors giving rise to skeletal and connective tissues, but these precursors have not previously been identified and characterized. Using human embryonic stem cells directed toward mesendodermal differentiation, we show …Bone tissue is continuously remodeled through the concerted actions of bone cells, which include bone resorption by osteoclasts and bone formation by osteoblasts, whereas osteocytes act as mechanosensors and orchestrators of the bone remodeling process. This process is under the control of local (e.g., growth …Discovery of human adult endothelial progenitor cells (EPCs) in 1997 revolutionized the concept of postnatal vasculogenesis [].Endothelial colony-forming cells (ECFCs) are now the consensus EPCs subtype with vasculogenic potential [].However, despite a huge interest for their future utilization as cell therapy … Because disruption of the regulation of bone-forming osteoblasts results in a variety of bone diseases, a better understanding of the origin of these cells by defining the mechanisms of bone development, remodeling, and regeneration is central to the development of novel therapeutic approaches. More particularly, there exists a close interaction and cross-talk mechanism between the bone forming cells (osteoblasts) the bone resorbing cells (osteoclasts) and the T cells of the adaptive immune system [ 4, 5 ]. In this review, we will focus on the interactions and cross-talk between various cells of the …Bone-forming cells originate from distinct embryological layers, mesoderm (axial and appendicular bones) and ectoderm (precursor of neural crest cells, which …Background Bone generation and maintenance involve osteoblasts, osteoclasts, and osteocytes which originate from unique precursors and rely on key growth factors for differentiation. However, an incomplete understanding of bone forming cells during wound healing has led to an unfilled clinical need such as …Benign bone tumors contain two main categories: bone-forming lesions (e.g., osteoid osteoma, osteoblastoma) and cartilage-forming lesions (e.g., osteochondroma, enchondroma) . The cell origin of bone tumors remains elusive. However, evidence suggests that SSCs or their progeny may be an important source of …The cells can be removed as liquid (to perform a smear to look at the cell morphology) or they can be removed via a core biopsy (to maintain the architecture or relationship of the cells to each other and to the bone). [citation needed] Subtypes. A colony-forming unit is a subtype of HSC.The cranial (cephalic) neural crest, whose cells migrate dorsolaterally to produce the craniofacial mesenchyme that differentiates into the cartilage, bone, cranial neurons, glia, and connective tissues of the face.These cells enter the pharyngeal arches and pouches to give rise to thymic cells, odontoblasts of the tooth primordia, and the bones of middle …Osteoblasts originate from osteoprogenitor cells, and transcription factors such as the runt related transcription factor two (RUNX2) ... The bone forming cells are osteoblasts that derive from the mesenchyme or ectomesenchyme and transform into osteocytes after their complete embedment into the …Recent findings. Langerhans cells (LCs) originate pre-natally and may endure throughout life, independently of bone marrow derived precursors. Fate mapping experiments have recently resolved the relative contribution of primitive yolk sac and fetal liver hematopoiesis to the initial formation of LCs. In post-natal life, local self …Engineering Vascular Niche for Bone Tissue Regeneration. Johnathan Ng, ... Gordana Vunjak-Novakovic, in Biology and Engineering of Stem Cell Niches, 2017. 2.2 Sources of Autologous Cells for Bone Formation. Osteoprogenitor cells isolated from bone and periosteum have been cultured on porous scaffolds to form bone …The bone marrow provides a framework of microenvironmental domains or niches that support the function of immune cells and haematopoietic stem cells (HSCs). Cellular niches are functional ...Dec 29, 2022 · Osteoprogenitor cells, also known as osteogenic cells, are stem cells in the bone that play a prodigal role in bone repair and growth.[1] These cells are the precursors to the more specialized bone cells (osteocytes and osteoblasts) and reside in the bone marrow. Osteoprogenitor cells originate from infant mesenchymal cells and turn into spindle cells at the surface of matured bones. In ... Types of Bone Cells: The bones are a core founding component of a living body that holds the structure of muscles and organs.The bones of the skeletal system is composed of two types of tissues, i.e., compact and spongy bone tissue.. The Compact bone tissue covers the outer part of the bone structure and …In adult mice pulsed at embryonic stages (E7.5, or E8.5, or E9.5 or E10.5), bone marrow HSC-derived progenitors, peripheral cells (T and B cells, and granulocytes) in the spleen, and CD11b hi F4 ...Growing new bones (bone formation). Reshaping bones to help them change as you age (remodeling). Healing damaged or broken bones. Osteoblasts are triggered by chemical …Metastatic cancer is a type of cancer that has spread from the original point of cancer to another place in the body, according to the National Cancer Institute at the National Ins...The osteoprogenitor cells originate from mesenchymal stem cells and differentiate to form osteoblasts. Osteoprogenitor cells are found on the external and internal surfaces of bones. They may also reside in the microvasculature supplying bone. ... Bone-forming cells that secrete unmineralized bone matrix called osteoid are …Benign bone tumors contain two main categories: bone-forming lesions (e.g., osteoid osteoma, osteoblastoma) and cartilage-forming lesions (e.g., osteochondroma, enchondroma) . The cell origin of bone tumors remains elusive. However, evidence suggests that SSCs or their progeny may be an important source of …Introduction. Interaction between different cell types is fundamental for development, repair and regeneration. In bone, recent data has uncovered that interactions between immune-regulated monocyte/macrophage lineage cells (osteoclasts) and mesenchymal cells that form the structural components of …Bone homeostasis is a complex process, requiring the precise coordination between bone-forming and bone-resorbing cells. Osteoclasts (OC) are the only cells that can efficiently resorb bone. Pathologic regulation of OC formation and function contributes to the development of diseases, like inflammatory …The cell responsible for bone resorption, or breakdown, is the osteoclast. They are found on bone surfaces, are multinucleated, and originate from monocytes and macrophages, two types of white blood … Briefly explain how the structure of each of these tissues is well suited to its function: stratified squamous epithelium in the skin, neurons in the brain, simple squamous epithelium lining the lung, bone in the skull. For each of the following, explain how structure relates to function: absorptive sections of the digestive tract; capillaries ... The first discovered source was the bone marrow, which was confirmed by Till and McCulloch. Very few HSCs can actually be extracted from bone marrow as only one in 10,000 cells is a long-term blood-forming cell. Another source of HSCs is in the peripheral blood (newly formed blood leaving the bone …Discovery of human adult endothelial progenitor cells (EPCs) in 1997 revolutionized the concept of postnatal vasculogenesis [].Endothelial colony-forming cells (ECFCs) are now the consensus EPCs subtype with vasculogenic potential [].However, despite a huge interest for their future utilization as cell therapy …Hematopoietic stem cells (HSCs) and an earlier wave of definitive erythroid/myeloid progenitors (EMPs) differentiate from hemogenic endothelial cells in the conceptus. EMPs can be generated in vitro from embryonic or induced pluripotent stem cells, but efforts to produce HSCs have largely failed. The formation of both EMPs and …When these cells are plated at low density, bone marrow stromal cells (BMSCs) rapidly adhere and can be easily separated from the nonadherent hematopoietic cells by repeated washing. With appropriate culture conditions, distinct colonies are formed, each of which is derived from a single precursor …The diaphysis is the tubular shaft that runs between the proximal and distal ends of the bone. The hollow region in the diaphysis is called the medullary cavity, which is filled with yellow marrow. The walls of the diaphysis are composed of dense, hard compact bone. Figure 5.3.1 5.3. 1: Anatomy of a Long Bone.Apr 4, 2022 · Introduction. Interaction between different cell types is fundamental for development, repair and regeneration. In bone, recent data has uncovered that interactions between immune-regulated monocyte/macrophage lineage cells (osteoclasts) and mesenchymal cells that form the structural components of bone (osteoblasts) are crucial for normal bone homeostasis and its successful repair (Ambrosi et ... Sep 29, 2023 · Bone is a living structure that grows, develops, and is continually modified during life due to the coordinated functions of its cells—osteoblasts, osteocytes, and osteoclasts. The coordinated actions of osteoblasts (bone-forming cells) and osteoclasts (bone-absorbing cells) allow bone tissue to repair itself, after a fracture, without scarring. Bone tissue is continuously remodeled through the concerted actions of bone cells, which include bone resorption by osteoclasts and bone formation by osteoblasts, …Myeloma (also called multiple myeloma) is a cancer that forms in white blood cells. It typically affects the bones as the cancerous cells accumulate in a person’s bone marrow. Myel...Nov 27, 2019 · Osteoclasts originate from hematopoietic stem cells (HSC), which are contained in the bone marrow. These are the same stem cells which produce all other types of blood cell, including red blood ... Nov 9, 2023 · Although lymphocytes have secondary sites of maturation, all these cells originate in the bone marrow. Lymphoblast. Lymphoblasts are the earliest identifiable lymphoid cells. They are large, mononuclear and undergoes division at least twice before forming prolymphoblasts. Prolymphoblast and lymphocyte. These prolymphoblasts then become ... Abstract. In endochondral bone development, bone-forming osteoblasts and bone marrow stromal cells have dual origins in the fetal cartilage and its surrounding perichondrium. However, how early ...Two types of white blood cells, T and B cells ( lymphocytes ), are also produced in the lymph nodes and spleen, and T cells are produced and mature in the thymus gland. (See also Overview of Blood .) Within the bone marrow, all blood cells originate from a single type of unspecialized cell called a stem cell. When a …Results. During the reversal-resorption phase, osteoclasts are intermixed with (COL3A1 + NFGR +) osteoblastic reversal cells, which are considered to be osteoprogenitors of (COL1A1 + SP7 +) bone-forming osteoblasts.Initiation of bone formation requires a critical density of these osteoprogenitors (43 ± 9 cells/mm), which …Specialized bone cells (i.e., the osteoblasts and osteocytes) originate from osteoprogenitor cells in the bone marrow. Osteoclasts do not develop from osteogenic … A) the lining of the medullary cavity. B) the bone type forming the shaft. C) is the covering of bone surfaces that form joints with other bones. D) also called the shaft. A) the lining of the medullary cavity. Bone forming cells originate from: A) osteocytes. B) osteoclasts. C) osteoblasts. Tagged: Bone, Cells, Mitosis. Osteoprogenitor cells, also known as osteogenic cells, are stem cells located in the bone that play a prodigal role in bone repair and growth. These cells are the precursors to the more specialized bone cells (osteocytes and osteoblasts) and reside in the bone marrow. Because disruption of the regulation of bone-forming osteoblasts results in a variety of bone diseases, a better understanding of the origin of these cells by defining the mechanisms of bone development, remodeling, and regeneration is central to the development of novel therapeutic approaches. BL-CFC describes a population of single-celled (clonal) precursors that gives rise to cell colonies with both HSC and endothelial features. When ES-cell-derived Flk-1-expressing (Flk-1 +) mouse cells are grown in culture, characteristic colonies appear, which consist of an aggregate of non-adherent HSCs overlying …Nov 27, 2019 · Osteoclasts originate from hematopoietic stem cells (HSC), which are contained in the bone marrow. These are the same stem cells which produce all other types of blood cell, including red blood ... Issues of Concern. Bone is a specialized connective tissue consisting of cells and a mineralized extracellular matrix, that is continuously being remodeled through a dynamic process to maintain structural integrity and shape. Under normal physiologic conditions, bone homeostasis is maintained through four distinct cell types: …Jan 14, 2024 · Osteoblasts. Osteoblast is the bone cells that are responsible for bone forming, they appear as cuboid cells aligned in layers along immature osteoid. Osteoblast activity stimulated by intermittent exposure to parathyroid hormone (PTH). While its activity inhibited by tumor necrosis factor (TNF)-α. The function of red blood cells is to. both carry carbon dioxide from the cells to the lungs and carry oxygen from the lungs to the body's cells. In adults, red bone marrow is located in the. sternum and ribs and iliac crest, body of vertebrae only. Which of the following vitamins is needed for the formation of clotting factors?Replacement of nonvascular cartilage by bone and bone marrow is a critical step in bone development. In a recent issue of Developmental Cell, Maes et al., 2010. report that a distinct population of immature precursors of bone-forming cells migrate into the cartilage in intimate association with invading blood vessels.Bone formation by osteoblasts and resorption by osteoclasts are tightly regulated processes responsible for continuous bone remodeling. Osteoclasts originate from hematopoietic stem cell ...HSCs live inside our bone marrow and keep making new blood cells throughout life. That’s why you don’t have to worry if you cut yourself and lose some blood – your bone marrow will make new cells very quickly. In fact, a single haematopoietic stem cell has the potential to make all 6 pints of your blood! As it …The cell responsible for bone resorption, or breakdown, is the osteoclast. They are found on bone surfaces, are multinucleated, and originate from monocytes and macrophages, two types of white blood …Textus osseous compactus. 1/7. Synonyms: Cortical bone, Substantia compacta. The strength, shape and stability of the human body are dependent on the musculoskeletal system. The most robust aspect of this unit is the underlying bony architecture. Bone is a modified form of connective tissue which …Discovery of human adult endothelial progenitor cells (EPCs) in 1997 revolutionized the concept of postnatal vasculogenesis [].Endothelial colony-forming cells (ECFCs) are now the consensus EPCs subtype with vasculogenic potential [].However, despite a huge interest for their future utilization as cell therapy …Nov 1, 2014 · Bone-forming cells originate from distinct embryological layers, mesoderm (axial and appendicular bones) and ectoderm (precursor of neural crest cells, which mainly form facial bones). These cells will develop bones by two principal mechanisms: intramembranous and endochondral ossification. In both … The cranial (cephalic) neural crest, whose cells migrate dorsolaterally to produce the craniofacial mesenchyme that differentiates into the cartilage, bone, cranial neurons, glia, and connective tissues of the face.These cells enter the pharyngeal arches and pouches to give rise to thymic cells, odontoblasts of the tooth primordia, and the bones of middle …By the 12th week of gestation, high proliferative potential colony forming cells (HPP-CFC) ... Although lymphocytes have secondary sites of maturation, all these cells originate in the bone marrow. Lymphoblast. Lymphoblasts are the earliest identifiable lymphoid cells. They are large, … Within the bone marrow, all blood cells originate from a single type of unspecialized cell called a stem cell. When a stem cell divides, it first becomes an immature red blood cell, white blood cell, or platelet-producing cell. The immature cell then divides, matures further, and ultimately becomes a mature red blood cell, white blood cell, or ... They are found on bone surfaces, are multinucleated, and originate from monocytes and macrophages, two types of white blood cells, not from osteogenic cells. …Nanosized biomineral precursors (≈30 nm in diameter), which originate from mitochondrial granules, initiate intrafibrillar mineralization of collagen as early as embryonic day 14.5. Both in vivo and in vitro studies further reveal that formation of mitochondrial granules is induced by the ER. ... Bone-forming cells, …7-4. T cells also originate in the bone marrow, but all the important events in their development occur in the thymus. T lymphocytes develop from a common lymphoid progenitor in the bone marrow that also gives rise to B lymphocytes, but those progeny destined to give rise to T cells leave the bone marrow and migrate to the …Holy Cross of Davao College, Inc. MAPEH 222. document. Chap 10 Group 4 P3.pdf. Great Neck North High School. SCIENCE AP PHYSICS. See more documents like this. Bone forming cells originate from osteoprogenitor cells The twisting of a long from BIOL 2457 at University of Texas, Arlington. Introduction. Osteoblasts –– “bone forming cells” in Greek –– are the only cells that can give rise to bones in vertebrates. They find that these colonies form in two stages. First, after 36–48 hours of 'plating' Flk-1 + cells for growth in culture, the cells form tightly adherent clusters. Subsequently, round, non ...Nov 9, 2023 · Although lymphocytes have secondary sites of maturation, all these cells originate in the bone marrow. Lymphoblast. Lymphoblasts are the earliest identifiable lymphoid cells. They are large, mononuclear and undergoes division at least twice before forming prolymphoblasts. Prolymphoblast and lymphocyte. These prolymphoblasts then become ... Osteocytes. bone maintenance cells. It is believed that they monitor the force on the bone and communicate with the brain and vascular system in order to request more calcium deposition in the bone around them. Osteoclast. type of cell that softens the calcium layers deposited around the compact bone. It is a cousin of a macrophage (phagocytic ... Jul 13, 2015 · Bone tissue is continuously remodeled through the concerted actions of bone cells, which include bone resorption by osteoclasts and bone formation by osteoblasts, whereas osteocytes act as mechanosensors and orchestrators of the bone remodeling process. This process is under the control of local (e.g., growth factors and cytokines) and systemic ... OSTEOBLASTS are the cells that form new bone. They also come from the bone marrow and are related to structural cells. They have only one nucleus. Osteoblasts work in …OSTEOCLASTS are large cells that dissolve the bone. They come from the bone marrow and are related to white blood cells. They are formed from two or more cells that fuse together, so the osteoclasts usually have more than one nucleus. They are found on the surface of the bone mineral next to the dissolving bone.Bone-forming cells are known as (a)Chondroclasts(b)Osteoblasts(c)Chondroblasts(d)Osteoclasts. Ans: Hint: The major cellular part of the bone is the bone-forming cells. They originate from the mesenchymal stem cells (MSC). MSC, along with adipocytes,...They find that these colonies form in two stages. First, after 36–48 hours of 'plating' Flk-1 + cells for growth in culture, the cells form tightly adherent clusters. Subsequently, round, non ... Osteocytes. bone maintenance cells. It is believed that they monitor the force on the bone and communicate with the brain and vascular system in order to request more calcium deposition in the bone around them. Osteoclast. type of cell that softens the calcium layers deposited around the compact bone. It is a cousin of a macrophage (phagocytic ... HSCs live inside our bone marrow and keep making new blood cells throughout life. That’s why you don’t have to worry if you cut yourself and lose some blood – your bone marrow will make new cells very quickly. In fact, a single haematopoietic stem cell has the potential to make all 6 pints of your blood! As it …Four types of bone cells are osteoblasts, osteocytes, osteoclasts, and bone lining cells. Osteoblasts are formed from osteogenic or osteoprogenitor cells, and further transform into osteocytes ...Angioblast → Endothelial cell. Mesangial cell. Intraglomerular. Extraglomerular. Juxtaglomerular cell. Macula densa cell. Stromal cell → Interstitial cell → Telocytes. Simple epithelial cell → Podocyte. Kidney proximal tubule brush border cell.(a) Mesenchymal cells group into clusters, differentiate into osteoblasts, and ossification centers form. (b) Secreted osteoid traps osteoblasts, which then become osteocytes. (c) …(ID: 3ef5d367f39b4a4e94a003645647f8dd) Learning Objectives. By the end of this section, you will be able to: Identify the anatomical features of a bone. Define and list examples … Briefly explain how the structure of each of these tissues is well suited to its function: stratified squamous epithelium in the skin, neurons in the brain, simple squamous epithelium lining the lung, bone in the skull. For each of the following, explain how structure relates to function: absorptive sections of the digestive tract; capillaries ... Interestingly, when compared to the cells isolated from the central part of the ganglion, the BC cells displayed a significantly higher number of clone-forming stem cell-like cells 30.Among the three embryonic germ layers, the mesoderm is a major source of the mesenchymal precursors giving rise to skeletal and connective tissues, but these precursors have not previously been identified and characterized. Using human embryonic stem cells directed toward mesendodermal differentiation, we show …Osteoclasts originate from hematopoietic stem cells (HSC), which are contained in the bone marrow. These are the same stem cells which produce all other types of blood cell, including red blood ...OSTEOBLASTS are the cells that form new bone. They also come from the bone marrow and are related to structural cells. They have only one nucleus. Osteoblasts work in …2.1 Bone Formation. Ossification (or osteogenesis) is the process of formation of new bone by cells called osteoblasts. These cells and the bone matrix are the two most crucial elements involved in the formation of bone. This process of formation of normal healthy bone is carried out by two important processes, namely:The adult blood-forming cells, whose origin in the early-stage embryo is unknown, are separately generated in the aorta–gonad–mesonephros (AGM) region and later seed the adult bone marrow. b ...Sep 2, 2011 · Figure 1. The origin of bone. Precipitation of hydroxyapatite around the basal membrane of the skin gave rise to enamel- and dentine-like tissues that formed odontodes, which became the progenitors of teeth and scales. Spread of mineralization deeper in the dermis formed shields consisting of acellular—and later cellular—bone. osteoblast, large cell responsible for the synthesis and mineralization of bone during both initial bone formation and later bone remodeling. Osteoblasts form a closely packed sheet on the surface of the bone, from which cellular processes extend through the developing bone. They arise from the differentiation of osteogenic cells in the ... 1/3. Synonyms: none. Osteoblasts are bone-forming cells derived from osteoprogenitor stem cells which arise from mesenchymal tissue. They are mostly located in the periosteum and the endosteum but may also occur within compact bone, in regions of remodeling. Histologically, active osteoblasts, which are engaged in bone matrix … | Cnzlmaqg (article) | Mjfqbdd.